The UNC/LCCC Protocol Office is an established clinical facility designed to serve as a core resource for the development and conduct of oncology clinical research for investigators in all disciplines. The Protocol Office staff, are responsible for protecting the safety of patients, ensuring the quality of the research, and safeguarding the interests of the University. The Protocol Office provides administrative, regulatory, data management, and study coordination services to investigators throughout the process of development, approval and implementation of protocols conducted at UNC-CH and its affiliate institutions. The Protocol Office also provides guidance and input focused on clinical research systems de