UC DAVIS GENOME CENTER Supervisor: Dr. Luis Carvajal-Carmona
An Assistant/Associate Specialist position is available in the laboratory of Professor Luis Carvajal-Carmona. The Carvajal-Carmona laboratory is located in the UC Davis Genome Center, a state-of-the-art genomic research facility, http://carvajal.genomecenter.ucdavis.edu.
The rank and step of this appointment will be determined based on the qualifications and experience of the successful candidate.
RESEARCH IN SPECIALIZED AREAS (70% EFFORT)
In direct collaboration with the Principal Investigator(s), this position will be involved in the establishment and characterization of minority patient-derived cancer models to elucidate clinically relevant molecular subtypes, drug targets and biomarkers for improved cancer treatment and precision medicine, with the ultimate goal of addressing cancer health disparities.
The candidate will specifically participate in establishing, maintaining and characterizing 2D and 3D cell cultures from human tumor biopsies and subsequent patient-derived xenografts (PDXs). Specific tasks will include maintaining primary and established tissue cultures, performing standard cancer cellular phenotypic assays, drug screens, transient transfections and single-cell cloning. The candidate must be familiar and able to learn quickly diverse molecular and genomic techniques, including but not limited to: whole-genome and whole-exome sequencing, RNA-sequencing, quantitative Real Time PCR (RT-qPCR), Taqman and KASP genotyping and chromatin approaches such as ChIP and Hi-C.
The candidate will assist in the preparation of manuscripts for publications, in collaboration with her/his direct supervisor. Manuscript preparation by the candidate will include reviewing the relevant literature and summarizing these reviews in the introduction, describing results and methods used to acquire the results, presenting and analyzing data obtained by the candidate, constructing clear and informative figures, interpreting the results and discussing how they fit in the current understanding of the field. Depending on whether the candidate is first or middle author of the manuscript in preparation, she/he will contribute these items for most of the manuscript or only the part contributed.
LABORATORY MANAGER (20%)
The Assistant/Associate Specialist will oversee general laboratory management and act as the major laboratory representative for communication with vendors, safety inspectors and Genome Center purchasing staff. Specific tasks will include maintenance of laboratory equipment, ordering and maintenance of laboratory supplies, maintenance of safety compliance by laboratory staff and scheduling of laboratory staff meetings.
PROFESSIONAL COMPETENCE AND ACTIVITY (5%)
Depending on interest and availability of funds, the Assistant/Associate Specialist will have opportunities to present research findings to a larger audience at meetings on the UC Davis campus. The candidate will also assist the investigator in presenting progress reports and final summaries to granting agencies, participate in appropriate professional/technical societies or groups and other educational and research organizations, and review research proposals, journal manuscripts, and publications related to area of expertise.
UNIVERSITY AND PUBLIC SERVICE (5%)
The Assistant/Associate Specialist will participate in training activities, such as mentoring undergraduate students. She/he will actively contribute to lab activities via meetings and unit/campus presentations. She/he may maintain liaisonship and respond to the needs of various industry organizations, state and federal agencies, and other external groups on issues related to area of expertise. The candidate will participate in activities of committees within the department, college, campus and other University entities, as appropriate.
UC Davis is the home of the Aggies — go-getters, change makers and problem solvers who make their mark at one of the top public universities in the United States. Since we first opened in 1908, we’ve been known for standout academics, sustainability and Aggie Pride as well as valuing the Northern California lifestyle. These themes are woven into our 100-plus-year history and our reputation for solving problems related to food, health, the environment and society.Our 5,300-acre campus is in the city of Davis, a vibrant college town of about 68,000 located in Yolo County. The state capital is 20 minutes away, and world-class destinations such as the San Francisco Bay Area, Lake Tahoe and the Napa Valley are within a two-hour drive.